Too little or too much testosterone may matter for heart rhythm

Original source summary

A review of clinical trials, observational studies, genetic analyses, and mechanistic research suggests that atrial fibrillation risk may follow a U-shaped relationship with testosterone, increasing at both low and high levels. Evidence on testosterone replacement therapy remains mixed, with researchers calling for prospective studies to determine whether mid-physiological testosterone targets and treatment formulation influence AF risk.

Verbatim from News-Medical's own feed — "Too little or too much testosterone may matter for heart rhythm"