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American journal of obstetrics and gynecology

May 21, 2026 · via Europe PMC

Pelvic floor symptoms after second-degree tear or episiotomy and the consequences of healing complications: long-term follow-up after the REPAIR study.

Perslev K, Klarskov N, Bergholt T, Jangö H.

Randomized Controlled TrialOpen access

AI summary — for doctors, generated from the abstract only

Pelvic floor symptoms were common 9-12 months after second-degree tears or episiotomy, and women with wound complications reported more sexual, prolapse and body image symptoms.

What was studied

Long-term follow-up of the single-center Danish REPAIR randomized trial (442 women with second-degree tear or episiotomy), using a pelvic floor questionnaire (n=378) and clinical examination (n=362).

Key findings

  • 12% (51/433) had a clinically relevant wound complication
  • Pelvic floor symptoms common across incontinence, prolapse and sexual domains
  • Wound complications associated with more sexual function and prolapse symptoms and lower body image scores, persisting after adjustment
  • Diagnostic prolapse more frequent with complications, but anatomical prolapse and pelvic floor measures similar

Clinical relevance

This supports attention to preventing perineal wound complications and to follow-up of affected women for pelvic floor symptoms.

Who should care

Obstetrics & GynaecologyGynaecological Oncology

Limitations

Single-center observational follow-up within a trial; association does not prove that complications cause symptoms.

Perineal wound complications after childbirth are linked to lasting pelvic floor and sexual symptoms.

This is an AI-generated summary of the published abstract, not a clinical recommendation. It may not reflect the full text or subsequent updates — verify against the original source before acting on it.

Abstract

Background

Prophylactic antibiotics reduce the risk of wound complications after second-degree perineal tears and episiotomy. However, the long-term consequences of experiencing a wound complication remain poorly studied.

Objective

(1) To evaluate the frequency of pelvic floor symptoms after second-degree tear and episiotomy and (2) to evaluate whether women who developed a wound complication had more pelvic floor symptoms 9 to 12 months postpartum compared to women without wound complications.

Study design

This study is a long-term follow-up of participants enrolled in the REPAIR study, a single-center, placebo-controlled, randomized trial conducted at a university hospital in Denmark. The original trial enrolled 442 women with a second-degree perineal tear or episiotomy to assess the effect of prophylactic antibiotics on wound complications. Long-term outcomes were assessed using 2 data sources: a pelvic floor questionnaire and a late postpartum follow-up clinical examination. Analyses of questionnaire-based outcomes included all women who completed the pelvic floor questionnaire regardless of attendance to the clinical examination. Analyses of outcomes from the clinical examination were restricted to women who attended the late postpartum follow-up visit.

Results

Of the 442 women included in the REPAIR study, 433 had information on wound healing status, of whom 51 (12%) experienced a clinically relevant complication. A total of 378 women completed the pelvic floor questionnaire and 362 attended the late postpartum follow-up. Pelvic floor symptoms were common across incontinence, prolapse, and sexual domains. Women with wound complications reported higher prevalences of symptoms, particularly related to sexual function, prolapse, and lower body image scores. This remained stable after adjustment for obstetric factors associated with wound complications. In the clinical examination, diagnostic prolapse was more frequent among women with wound complications, while anatomical prolapse and pelvic floor measurements were similar between groups.

Conclusion

Pelvic floor symptoms were common 9 to 12 months after second-degree tears or episiotomy. Women with postpartum wound complications reported more symptoms, particularly related to sexual function, prolapse, and body image. These findings suggest that wound healing is associated with long-term pelvic floor health and support attention to prevention and follow-up.

DOI

10.1016/j.ajog.2026.05.009

PMID

42173186

Research metadata (titles, abstracts, authors, publication dates) is sourced from Europe PMC, which aggregates content from PubMed/MEDLINE, PubMed Central, and other providers under the U.S. National Library of Medicine (NLM/NCBI). NLM does not claim copyright on abstracts; the original journal publishers or authors may hold rights to the full articles. AI-generated summaries are derived only from the abstract, never the full text, and are always labeled as AI-generated.

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