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Journal of clinical and experimental hepatology

June 26, 2026 · via Europe PMC

Application of 3D Reconstruction Software for Preoperative Evaluation of Split and Living Donor Liver Volume in Liver Transplantation.

Wang S, Muhammad I, Wang Y, +12 more, Wang F.

Journal ArticleAbstract only — full text under license

AI summary — for doctors, generated from the abstract only

A study using 3D reconstruction software for preoperative CT-based liver volume planning in split and living donor liver transplantation found no statistically significant difference between estimated and actual intraoperatively measured graft volumes across all graft types studied.

What was studied

A study using Hisense computer-assisted surgery (CAS) software to create 3D reconstructions of donor livers from CT images for 62 donors and 80 recipients, comparing preoperatively estimated graft volumes (left lateral lobe, extended right half, left half, right half) against intraoperatively measured volumes, and monitoring postoperative donor liver volume regeneration.

Key findings

  • 3D reconstructions were successfully generated for all 62 donors and 80 recipients across graft types: left lateral lobe (27 cases), extended right half graft (21 cases), left half (14 cases), and right half (18 cases).
  • There were no statistically significant differences between preoperatively estimated and intraoperatively measured volumes for any of the graft types studied.
  • Following transplantation, donor liver volume was found to have regenerated to near-normal volume by one month post-transplant.

Clinical relevance

The findings suggest that 3D reconstruction software can provide accurate preoperative estimation of donor liver graft volume across different graft types, which may support more precise surgical planning in split and living donor liver transplantation.

Who should care

HepatologyMedical Gastroenterology

Limitations

Important limitations may not be assessable from the abstract alone; this was a relatively small, single-technology study without comparison to other volumetric estimation methods.

3D reconstruction software accurately predicted donor liver graft volumes across multiple graft types compared with actual measured volumes, supporting its use for precise preoperative surgical planning.

This is an AI-generated summary of the published abstract, not a clinical recommendation. It may not reflect the full text or subsequent updates — verify against the original source before acting on it.

Abstract

Background and aim

The effectiveness of liver transplantation depends on the precise estimation of the donors' liver volume, particularly in split and living donor liver transplantation. In this study, the volume of the split donor liver graft was assessed, and accurate surgical planning was performed using the Hisense computer-assisted surgery system (Hisense CAS).

Methods

Based on computed tomography images, we used Hisense CAS to reconstruct the donor liver and generate clear 3D images of donor liver volume, vessels, and bile ducts. Subsequently, the volumes of the split liver grafts, including the left lateral lobe, extended right half graft, left half, and right half, were measured. These measurements were then compared with the intraoperatively measured volumes. We also used the system to monitor postoperative changes in liver volume regeneration.

Results

We effectively reconstructed 3D images of 62 donors and 80 recipients, and compared the preoperatively estimated volumes with the intraoperatively measured volumes for the following graft types: left lateral lobe in 27 cases (living donor, 15 cases; donation after brain death [DBD], 12 cases), extended right half graft in 21 cases (DBD, 21 cases), left half in 14 cases (living donor, 7 cases; DBD, 7 cases), and right half in 18 cases (living donor, 11 cases; DBD, 7 cases). There were no statistically significant differences between the estimated and measured volumes for any graft type. Following split and living donor liver transplantation, the donor liver volume was monitored, and the results showed that one month after transplantation, the donor liver volume regenerated to near-normal liver volume.

Conclusion

Our results showed that donor liver volume can be precisely determined using 3D reconstruction software (Hisense CAS). There were no statistically significant differences between the volume estimated by reconstruction and the actual volume measured intraoperatively.

DOI

10.1016/j.jceh.2026.103594

PMID

42502372

Research metadata (titles, abstracts, authors, publication dates) is sourced from Europe PMC, which aggregates content from PubMed/MEDLINE, PubMed Central, and other providers under the U.S. National Library of Medicine (NLM/NCBI). NLM does not claim copyright on abstracts; the original journal publishers or authors may hold rights to the full articles. AI-generated summaries are derived only from the abstract, never the full text, and are always labeled as AI-generated.

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