Thorax
September 18, 2026 · via Europe PMC
Establishing the top 10 research priorities for lung volume reduction treatment for people with COPD.
Buttery SC, Barraclough R, Batchelor TJP, +16 more, LVR-PSP steering group.
AI summary — for doctors, generated from the abstract only
A structured priority-setting exercise involving patients and healthcare professionals identified 10 key research questions to guide future study of lung volume reduction treatment for COPD, spanning patient selection, procedural technique, and post-procedure care.
What was studied
A research prioritization exercise using James Lind Alliance-based methodology, involving people with COPD and healthcare professionals across multiple disciplines, to identify the top 10 research priorities for lung volume reduction treatment, an established evidence-based component of COPD care.
Key findings
- Through an iterative prioritization process, the exercise identified a final set of 10 research priorities relevant to lung volume reduction treatment for COPD.
- The identified priorities address how to identify, assess, and optimize patients with COPD before any lung volume reduction procedure.
- Additional priorities address how lung volume reduction procedures themselves should be conducted and how post-procedure care should be organized.
Clinical relevance
The findings suggest that this patient- and clinician-informed priority list can help guide future research funding and study design toward the questions considered most important for improving patient selection, procedural approach, and aftercare in lung volume reduction treatment for COPD, potentially accelerating evidence generation in areas most relevant to real-world care and patient concerns.
Who should care
Limitations
This is a priority-setting exercise reflecting the views of participating patients and clinicians rather than new clinical outcome data itself; the specific 10 questions and their relative ranking were not detailed in the provided abstract, limiting assessment of their specific content here.
Patients and clinicians jointly identified the 10 most important unanswered research questions about lung volume reduction treatment for COPD, covering patient selection, procedure conduct, and aftercare.
This is an AI-generated summary of the published abstract, not a clinical recommendation. It may not reflect the full text or subsequent updates — verify against the original source before acting on it.
Abstract
Lung volume reduction procedures are an established evidence-based aspect of chronic obstructive pulmonary disease (COPD) care. We conducted a research prioritisation exercise involving people with COPD and healthcare professionals across a range of disciplines, to identify a clear set of 10 questions to guide the development of research proposals in this area. Priorities were identified using an iterative approach based on the James Lind Alliance methodology. The final set of 10 priorities address the identification, assessment and optimisation of patients with COPD prior to any procedure, how lung volume reduction procedures are conducted and how care after the procedure has taken place should be organised.
DOI
10.1136/thorax-2026-224791
PMID
42248680
Research metadata (titles, abstracts, authors, publication dates) is sourced from Europe PMC, which aggregates content from PubMed/MEDLINE, PubMed Central, and other providers under the U.S. National Library of Medicine (NLM/NCBI). NLM does not claim copyright on abstracts; the original journal publishers or authors may hold rights to the full articles. AI-generated summaries are derived only from the abstract, never the full text, and are always labeled as AI-generated.
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