Indian pediatrics
April 27, 2026 · via Europe PMC
Continuous Ambulatory Blood Pressure Monitoring of Non-Dialyzed Children and Adolescents with Chronic Kidney Disease.
Mahajan A, Lalramchuani C, Mantan M, Mehta V.
AI summary — for doctors, generated from the abstract only
In a study of non-dialyzed children with chronic kidney disease, continuous ambulatory blood pressure monitoring identified substantial rates of masked hypertension, white coat hypertension, and blunted nocturnal blood pressure dipping that would not have been captured by casual office blood pressure measurement alone.
What was studied
A study enrolling 74 adolescents aged 10-18 years with chronic kidney disease (excluding those on dialysis or with hypertensive urgency/emergency), comparing casual blood pressure measurement with continuous ambulatory blood pressure monitoring (CABPM) to characterize patterns of hypertension and nocturnal blood pressure dipping.
Key findings
- Using CABPM, 12 of 74 (16.2%) had white coat hypertension, 7 (9.5%) had masked hypertension, and 14 (18.9%) had ambulatory hypertension.
- 28 of 74 children (37.8%) had blunted nocturnal blood pressure dipping.
- 6.6% of children had left ventricular hypertrophy.
Clinical relevance
This may be relevant to pediatric nephrologists managing children with chronic kidney disease, suggesting that relying on casual office blood pressure alone could miss a substantial proportion of children with masked hypertension or abnormal nocturnal blood pressure patterns, both of which are relevant to long-term cardiovascular risk in this population.
Who should care
Limitations
This was a cross-sectional study with a modest sample size (74 adolescents) from what appears to be a single center, without long-term follow-up to confirm whether detected abnormalities (like masked hypertension or blunted dipping) translate into worse long-term cardiovascular or renal outcomes in this cohort.
Ambulatory blood pressure monitoring uncovered hidden (masked) hypertension and abnormal nighttime blood pressure patterns in a substantial minority of children with chronic kidney disease that casual office measurements would have missed.
This is an AI-generated summary of the published abstract, not a clinical recommendation. It may not reflect the full text or subsequent updates — verify against the original source before acting on it.
Abstract
Hypertension is a known complication and modifiable risk factor for chronic kidney disease (CKD). Diurnal variability is better assessed using continuous ambulatory blood pressure monitoring (CABPM). We enrolled 74 adolescents (78.4% boys) aged 10-18 years with CKD, excluding those on dialysis or with hypertensive urgency/emergency. Casual blood pressure and CABPM were measured using Omron oscillometric sphygmomanometer and A&D TM2441, respectively. Using CABPM, 12 (16.2%) had white coat hypertension, 7 (9.5%) had masked hypertension, and 14 (18.9%) had ambulatory hypertension. Twenty-eight (37.8%) children had blunted nocturnal dipping and 6.6% had left ventricular hypertrophy (LVH).
DOI
10.1007/s13312-026-00346-z
PMID
42043771
Research metadata (titles, abstracts, authors, publication dates) is sourced from Europe PMC, which aggregates content from PubMed/MEDLINE, PubMed Central, and other providers under the U.S. National Library of Medicine (NLM/NCBI). NLM does not claim copyright on abstracts; the original journal publishers or authors may hold rights to the full articles. AI-generated summaries are derived only from the abstract, never the full text, and are always labeled as AI-generated.
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