Cytopathology : official journal of the British Society for Clinical Cytology
June 20, 2026 · via Europe PMC
Psammoma Bodies in Cervical Liquid-Based Cytology of a Kyleena User.
Eleutério Junior J, de Souza VAA, Eleutério RMN.
AI summary — for doctors, generated from the abstract only
This case report describes an extremely rare finding of calcified structures (psammoma bodies) on a cervical Pap test in a woman using a specific hormonal IUD, adding to the very limited literature on this unusual, generally benign association.
What was studied
A single case report describing the identification of psammoma bodies (laminated calcified structures) on liquid-based cervical cytology in a woman using the Kyleena intrauterine device (IUD), an extremely rare finding in IUD users.
Key findings
- Psammoma bodies in Pap smears from IUD users are exceedingly rare, with previously reported prevalence ranging from only 0.0047% to 0.009% of cases.
- The laminated calcified structures were observed intermixed among squamous, glandular, and inflammatory cells on liquid-based cytology from the cervix.
- These findings were consistent with the characteristic appearance of psammoma bodies.
Clinical relevance
The findings add to the sparse existing literature documenting this rare, generally benign cytologic finding in IUD users, which is clinically relevant because pathologists should be aware that psammoma bodies can occasionally occur in this context without necessarily indicating malignancy, so as to avoid unwarranted concern or unnecessary further workup.
Who should care
Limitations
This is a single case report, so findings cannot be generalized to determine the broader significance or frequency of this association across different IUD types or patient populations.
A rare case of calcified structures (psammoma bodies) found on a cervical Pap test in an IUD user adds to the very limited literature on this unusual, generally benign cytologic finding.
This is an AI-generated summary of the published abstract, not a clinical recommendation. It may not reflect the full text or subsequent updates — verify against the original source before acting on it.
Abstract
Psammoma bodies in Pap smears from IUD users are rare, with reported prevalence ranging from 0.0047% to 0.009%. We observed laminated calcified structures among squamous, glandular and inflammatory cells on liquid-based cytology from the uterine cervix, features consistent with psammoma bodies.
DOI
10.1111/cyt.70101
PMID
42322105
PMCID
PMC13460460
Research metadata (titles, abstracts, authors, publication dates) is sourced from Europe PMC, which aggregates content from PubMed/MEDLINE, PubMed Central, and other providers under the U.S. National Library of Medicine (NLM/NCBI). NLM does not claim copyright on abstracts; the original journal publishers or authors may hold rights to the full articles. AI-generated summaries are derived only from the abstract, never the full text, and are always labeled as AI-generated.
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