Pediatric cardiology
September 11, 2026 · via Europe PMC
Fetal Echocardiography Enhances Perinatal Care for Coarctation of the Aorta: Balancing Risk of Hemodynamic Compromise and Resource Utilization.
Stave EA, Donofrio MT, Mehta R, Park IH, Goudar SP
AI summary — for doctors, generated from the abstract only
Fetal echo-based risk stratification for suspected coarctation safely sent low-risk babies to community postnatal assessment and reduced prostaglandin use and transfers.
What was studied
Retrospective study of 199 fetuses with suspected coarctation (2009-2023) assigned to level of care 1 (low risk) or 2 (moderate risk) using fetal echo measures, compared with postnatal outcomes.
Key findings
- 182 were assigned LOC 1 and 17 LOC 2; 6% of LOC 1 and 41.2% of LOC 2 needed coarctation repair.
- LOC 2 assignment became less frequent over time with a similar repair frequency.
- No increase in morbidity or hospital stay for repaired infants assigned LOC 1.
Clinical relevance
It supports a tiered pathway that avoids unnecessary prostaglandin and transport without worsening outcomes.
Who should care
Limitations
Retrospective single-center study with few LOC 2 patients and no clear control for practice changes over time.
Where a robust postnatal echo plan exists, consider tiered management of suspected coarctation rather than routine transfer and prostaglandin.
This is an AI-generated summary of the published abstract, not a clinical recommendation. It may not reflect the full text or subsequent updates — verify against the original source before acting on it.
Abstract
Prenatal diagnosis of coarctation of the aorta (CoA) remains challenging. Anticipated postnatal risk, level of care (LOC), was assigned using fetal echocardiography measures including mitral valve/tricuspid valve ratio, aortic valve/pulmonary valve ratio, and aortic isthmus size. Patients assigned LOC 1 (low risk, not expected to have instability within first weeks of life) underwent postnatal echocardiography in the community; patients assigned LOC 2 (moderate risk, expected stability at delivery, postnatal intervention before hospital discharge) were started on prostaglandin and transferred. We hypothesize that LOC assignment leads to minimal neonatal morbidity. Patients with prenatal suspicion of CoA (2009-2023) were studied comparing prenatal LOC with postnatal outcomes. Retrospective analyses were performed with chi-square or Fisher's exact test for categorical variables and t-test, Mann-Whitney, or Kruskal Wallis test for continuous variables. Of 199 fetuses, 182 were assigned LOC 1 and 17 LOC 2. Of patients assigned LOC 1, 6% (11/182) versus 41.2% (7/17) of patients assigned LOC 2 required CoA repair. Interestingly, over the study period, fewer patients were assigned LOC 2 despite similar frequency of patients requiring CoA repair, suggesting a practice change. There was no increase in morbidity or length of hospital stay in patients who required CoA repair assigned LOC 1 versus 2. LOC assignment for patients with suspected CoA, with a robust framework for postnatal assessment including postnatal echocardiogram at the delivery hospital, results in confidence in LOC assignment. The increase in LOC 1 assignment over time reduced prostaglandin use and unnecessary transport without increasing morbidity, even if surgery was needed.
DOI
10.1007/s00246-026-04463-1
PMID
42726232
Research metadata (titles, abstracts, authors, publication dates) is sourced from Europe PMC, which aggregates content from PubMed/MEDLINE, PubMed Central, and other providers under the U.S. National Library of Medicine (NLM/NCBI). NLM does not claim copyright on abstracts; the original journal publishers or authors may hold rights to the full articles. AI-generated summaries are derived only from the abstract, never the full text, and are always labeled as AI-generated.
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