JACC. Cardiovascular interventions
October 12, 2026 · via Europe PMC
Intraprocedural Cardiac Arrest in Patients Undergoing Percutaneous Coronary Interventions in the United States: An Analysis of the NCDR CathPCI Registry.
Mosarla RC, Shah B, Rao SV, Bangalore S, Manandhar P, Brothers L, Rymer J, Smilowitz NR
AI summary — for doctors, generated from the abstract only
Cardiac arrest during PCI occurred in about 0.93% of US procedures and became more frequent over time.
What was studied
Analysis of the NCDR CathPCI Registry, 2018 to 2023, covering about 3.96 million PCIs, examining incidence, mortality and predictors of intraprocedural cardiac arrest.
Key findings
- 36,755 arrests occurred (0.93%), 0.24% in elective and 1.28% in acute coronary syndrome PCI
- Incidence rose from 0.62% in 2018 to 1.07% in 2023
- Risk-adjusted in-hospital mortality declined slightly; several patient and procedural predictors were identified
Clinical relevance
Gives benchmark rates and highlights high-risk patients for whom cath labs should prepare for arrest.
Who should care
Limitations
Registry data with possible reporting changes over time; the abstract does not list the predictors or mortality figures.
Anticipate and plan for arrest in high-risk PCI, particularly in acute coronary syndromes.
This is an AI-generated summary of the published abstract, not a clinical recommendation. It may not reflect the full text or subsequent updates — verify against the original source before acting on it.
Abstract
BACKGROUND
Cardiac arrest (CA) during percutaneous coronary interventions (PCI) is a catastrophic procedural complication. Contemporary rates of CA during PCI are unknown.
OBJECTIVES
This study sought to understand contemporary rates of CA, associated mortality, and identify predictors of CA during PCI.
METHODS
Patients with CA during PCI from 2018 to 2023 were identified from the National Cardiovascular Data Registry CathPCI Registry. Trends in intraprocedural CA (IPCA) incidence and in-hospital death were evaluated. Predictors of IPCA and risk-adjusted mortality were identified.
RESULTS
A total of 36,755 IPCA occurred during 3,956,840 PCIs (0.93%), including in 0.24% of elective PCIs, 0.32% of PCIs for stable coronary artery disease, and 1.28% of acute coronary syndrome interventions. The incidence of IPCA increased over time (0.62% in 2018 to 1.07% in 2023; P < 0.0001). In-hospital death occurred in 40.5% of patients with IPCA, 45.4% of whom died in the cardiac catheterization laboratory. Notably, although risk-adjusted IPCA increased (0.79% to 0.95%; P = 0.042), slight declines in risk-adjusted mortality (45.1% to 43.6%; P = 0.027) were observed over time. PCI for ST-segment elevation myocardial infarction, non-ST-segment acute coronary syndromes, increasing age, ventricular arrhythmias, severe aortic stenosis, vasopressors or inotrope use, mechanical circulatory support, coronary perforation, coronary dissection, cardiac tamponade, intraprocedural heart failure or myocardial infarction, and temporary cardiac pacemaker implantation were associated with increased adjusted odds of IPCA.
CONCLUSIONS
IPCA complicates 0.93% of contemporary PCI. Despite an increasing incidence of risk-adjusted IPCA, there were slight declines in risk-adjusted in-hospital mortality in the study period. Several patient and procedural characteristics were independently associated with intraprocedural CA.
DOI
10.1016/j.jcin.2026.07.035
PMID
42863873
Research metadata (titles, abstracts, authors, publication dates) is sourced from Europe PMC, which aggregates content from PubMed/MEDLINE, PubMed Central, and other providers under the U.S. National Library of Medicine (NLM/NCBI). NLM does not claim copyright on abstracts; the original journal publishers or authors may hold rights to the full articles. AI-generated summaries are derived only from the abstract, never the full text, and are always labeled as AI-generated.
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