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Vaccine

October 15, 2026 · via Europe PMC

Understanding rotavirus vaccine acceptance in Indonesia: a WHO BeSD-based exploration of parents' and religious leaders' perspectives in three provinces.

Ekawati FM, Azizah AH, Lisa HRA, +8 more, Thobari JA.

Journal ArticleAbstract only — full text under license

AI summary — for doctors, generated from the abstract only

Rotavirus vaccine acceptance in three Indonesian provinces was high, driven by trust, with gaps in information and vaccine availability in remote areas.

What was studied

Qualitative study using the WHO BeSD framework: five focus groups and 24 in-depth interviews with 71 participants (61 parents, 10 religious leaders) in Yogyakarta, Bali and the Moluccas, from May to December 2025.

Key findings

  • Acceptance was high, driven by trust in vaccine benefits and confidence in health services.
  • Concerns about adverse effects and limited information persisted, especially in rural areas; health workers, community endorsement and religious leaders supported uptake.
  • Most mothers reported decision-making autonomy, though gender influences persisted in some households.

Clinical relevance

Supports tailored communication, engagement of religious leaders and addressing supply reliability in remote areas.

Who should care

Infectious DiseaseClinical Immunology & Rheumatology

Limitations

Qualitative and purposively sampled in three provinces, so findings are not statistically generalisable and uptake rates were not measured.

Acceptance is strong; better information and reliable supply would help.

This is an AI-generated summary of the published abstract, not a clinical recommendation. It may not reflect the full text or subsequent updates — verify against the original source before acting on it.

Abstract

Background

Disparities in rotavirus vaccine uptake in Indonesia persist despite its national implementation, yet, the community-level determinants of vaccination remain underexplored. Understanding the behavioural and social factors influencing vaccination decisions is essential for developing interventions that improve vaccine uptake in the community.

Methods

A qualitative study was conducted using the World Health Organization Behavioural and Social Drivers (WHO BeSD) framework. Data were collected between May and December 2025 through five focus group discussions and 24 in-depth interviews with parents and religious leaders in Yogyakarta, Bali, and the Moluccas. Participants were purposively sampled to capture diverse experiences and perspectives. Data were analysed using a deductive thematic approach guided by the four BeSD domains: Thinking and Feeling, Social Processes, Motivation, and Practical Issues.

Results

Seventy-one participants (61 parents and 10 religious leaders) took part in the study. Overall acceptance of rotavirus vaccination was high and driven by trust in vaccine benefits and confidence in health services. Within the Thinking and Feeling domain, participants recognised the severity of diarrhoeal disease and the protective value of vaccination, although concerns about adverse effects and limited access to information remained, particularly in rural areas. Social Processes generally supported vaccine uptake through health workers' recommendations, community endorsement, and support from religious leaders. Most mothers reported autonomy in vaccination decision-making, although gender-related influences persisted in some households. Motivation to vaccinate was strengthened by the desire to protect children from severe illness. Under Practical Issues, participants described vaccination services as accessible through primary healthcare facilities but highlighted the need for improved information dissemination and more reliable vaccine availability in remote areas.

Conclusions

Improving vaccine literacy, strengthening service delivery, and addressing practical barriers are critical to increasing complete rotavirus vaccination uptake. Tailored communication and engagement of parents, religious leaders, and community stakeholders may further enhance vaccine acceptance and uptake across diverse Indonesian settings.

DOI

10.1016/j.vaccine.2026.129211

PMID

42879900

Research metadata (titles, abstracts, authors, publication dates) is sourced from Europe PMC, which aggregates content from PubMed/MEDLINE, PubMed Central, and other providers under the U.S. National Library of Medicine (NLM/NCBI). NLM does not claim copyright on abstracts; the original journal publishers or authors may hold rights to the full articles. AI-generated summaries are derived only from the abstract, never the full text, and are always labeled as AI-generated.

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