Journal of clinical and experimental hepatology
September 8, 2026 · via Europe PMC
A Survey on Terminology and Diagnostic Features of a Subgroup of Non-cirrhotic Portal Hypertension Patients: A Report from Asia-Pacific Experts.
Shukla A, Qi X, Ormeci N, Duseja A, Sarin S.
AI summary — for doctors, generated from the abstract only
Asia-Pacific experts overwhelmingly favored keeping the NCPF/IPH terminology and a clinical, histological and portal hypertension-based diagnostic framework over the broader term porto-sinusoidal vascular disorder.
What was studied
An anonymised online questionnaire survey of 300 specialized experts in the Asia-Pacific region (242 respondents) on nomenclature, diagnostic features and staging for non-cirrhotic portal fibrosis/idiopathic portal hypertension.
Key findings
- 93.4% of respondents favored continued use of the NCPF/IPH nomenclature in daily practice
- 80.1% endorsed liver histopathology as a fundamental diagnostic component, and 95.9% agreed that a liver stiffness below the cirrhosis range with portal hypertension strongly suggests the condition
- 91% agreed with the APASL staging system
Clinical relevance
The survey supports regional practice using NCPF/IPH criteria that combine histology, elastography and portal hypertension, which may matter for guideline alignment.
Who should care
Limitations
Opinion survey data reflect expert views, not outcomes, and the response rate (242 of 300) and regional focus limit generalizability. It cannot settle the nomenclature question globally.
Asia-Pacific experts want to retain NCPF/IPH terminology and the APASL framework.
This is an AI-generated summary of the published abstract, not a clinical recommendation. It may not reflect the full text or subsequent updates — verify against the original source before acting on it.
Abstract
Background: There have been recent proposals to replace non-cirrhotic portal fibrosis (NCPF), idiopathic portal hypertension (IPH), idiopathic non-cirrhotic portal hypertension, nodular regenerative hyperplasia, etc. with an all-encompassing term "porto-sinusoidal vascular disorder." However, the Asia-Pacific Association for Study of the Liver recommended continued use of the term NCPF/IPH. Methods: We sent this questionnaire-based online survey to capture the clinical perspectives of 300 specialized experts in the Asia-Pacific region with complete anonymisation. Results: The survey (n = 242 respondents) revealed overwhelming support for the continued use of the NCPF/IPH nomenclature, with 93.4% of experts favoring the term in daily practice. Furthermore, 80.1% endorsed liver histopathology as a fundamental diagnostic component, while 95.9% agreed that a lower-than-cirrhosis-range liver stiffness measurement obtained via transient elastography in the presence of portal hypertension is highly indicative of the condition.A total of 91% agreed with the APASL staging system. Conclusions: The results highlight a persistent regional consensus favoring a clinical, histological and portal hypertension-driven diagnostic and staging framework for NCPF. The survey reveals strong support for the continued use of the NCPF/IPH nomenclature.
DOI
10.1016/j.jceh.2026.103671
PMID
42893017
Research metadata (titles, abstracts, authors, publication dates) is sourced from Europe PMC, which aggregates content from PubMed/MEDLINE, PubMed Central, and other providers under the U.S. National Library of Medicine (NLM/NCBI). NLM does not claim copyright on abstracts; the original journal publishers or authors may hold rights to the full articles. AI-generated summaries are derived only from the abstract, never the full text, and are always labeled as AI-generated.
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