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Annals of plastic surgery

August 4, 2026 · via Europe PMC

Patient-Centered Care in Gender-Affirming Surgical Reversal: A Case Report of Breast Reconstruction Using Autologous Fat Grafting and Discussion on Reversal, Detransition, and Regret.

Haley C, Roblee C, Lane M, Hsu J, Olinger T.

Case ReportsAbstract only — full text under license

AI summary — for doctors, generated from the abstract only

A case of surgical reversal without regret after gender-affirming mastectomy was managed with staged autologous fat grafting alone.

What was studied

Case report of breast reconstruction by staged autologous fat grafting after gender-affirming mastectomy, with a discussion distinguishing surgical reversal, detransition and regret.

Key findings

  • Staged fat grafting alone was used as a novel approach to reconstruct the breasts.
  • Reversal, detransition and regret are distinct concepts that do not always coincide.
  • The reported prevalence of reversal and regret is described as very low.

Clinical relevance

Surgeons caring for gender-diverse patients may meet requests for reversal and benefit from a patient-centred framework for these conversations.

Who should care

Plastic & Reconstructive Surgery

Limitations

A single case report with a narrative discussion, so it provides no comparative or generalisable outcome data.

Discuss reversal, detransition and regret as separate concepts and explore each patient's individual goals and perspective.

This is an AI-generated summary of the published abstract, not a clinical recommendation. It may not reflect the full text or subsequent updates — verify against the original source before acting on it.

Abstract

Utilization of gender-affirming surgery has increased significantly over the past 15 years, while the prevalence of surgical reversal and regret remains very low. Nonetheless, these phenomena have recently attracted considerable media and political attention. This report presents a case of surgical reversal without regret following gender-affirming mastectomy utilizing a novel approach using staged autologous fat grafting alone. We further explore the distinct concepts of surgical reversal, detransition, and regret, emphasizing patient-centered discussions to enhance understanding of patient perspectives. By fostering a comprehensive understanding of the patient experience and the complex interrelationships among detransitioning, surgical reversal, and regret, gender-affirming surgeons can deliver compassionate, affirming care throughout their patients' surgical experience.

DOI

10.1097/sap.0000000000004837

PMID

42554443

Research metadata (titles, abstracts, authors, publication dates) is sourced from Europe PMC, which aggregates content from PubMed/MEDLINE, PubMed Central, and other providers under the U.S. National Library of Medicine (NLM/NCBI). NLM does not claim copyright on abstracts; the original journal publishers or authors may hold rights to the full articles. AI-generated summaries are derived only from the abstract, never the full text, and are always labeled as AI-generated.

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