Journal of perinatology : official journal of the California Perinatal Association
March 20, 2026 · via Europe PMC
Catheter and echocardiographic-focused management of primary pulmonary vein stenosis in premature infants: a single center 5-year experience.
Nassetta K, O'Halloran CP, Hoyt E, +5 more, Hauck A.
AI summary — for doctors, generated from the abstract only
A percutaneous strategy with echocardiographic surveillance achieved good survival and vein preservation in premature infants with PVS.
What was studied
Single-center retrospective study of 15 premature infants (median 24 weeks) undergoing pulmonary vein intervention, 2018-2023.
Key findings
- Survival was 100% at 1 year and 89% at 2 years.
- Pulmonary vein preservation was 88% and 83% at 1 and 2 years.
- Surveillance used about 4 echocardiograms between catheterizations.
Clinical relevance
Suggests an aggressive approach can be feasible even in extremely preterm infants.
Who should care
Limitations
Very small single-center series without a comparison group.
Consider early catheter-based intervention with echo surveillance in centers with expertise.
This is an AI-generated summary of the published abstract, not a clinical recommendation. It may not reflect the full text or subsequent updates — verify against the original source before acting on it.
Abstract
Background/objectives
We describe the outcomes of pulmonary vein stenosis treatment in a cohort of premature infants using an assertive percutaneous management strategy with echocardiography as the primary method of surveillance.
Subjects/methods
This retrospective study included fifteen premature infants (median 24 weeks gestational age) that underwent pulmonary vein intervention from 2018-2023. The primary outcome was patient survival rate, and the secondary outcome was pulmonary vein preservation rate.
Results
The estimated patient survival was 100% and 89% at 1 and 2 years after diagnosis. The pulmonary vein preservation rate was 88% and 83% at 1 and 2 years. Patients received a median of 4 echocardiograms between each cardiac catheterization and an average of 1 CT scan for every 1.5 years of observation.
Conclusions
Pulmonary vein stenosis can be successfully managed with a percutaneous approach to pulmonary vein rehabilitation using echocardiography for surveillance, even in extremely premature infants.
DOI
10.1038/s41372-026-02611-2
PMID
41862593
PMCID
PMC13680283
Research metadata (titles, abstracts, authors, publication dates) is sourced from Europe PMC, which aggregates content from PubMed/MEDLINE, PubMed Central, and other providers under the U.S. National Library of Medicine (NLM/NCBI). NLM does not claim copyright on abstracts; the original journal publishers or authors may hold rights to the full articles. AI-generated summaries are derived only from the abstract, never the full text, and are always labeled as AI-generated.
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