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Neurourology and urodynamics

July 6, 2026 · via Europe PMC

Advancing Personalized Care for Neurogenic Bladder: The Case for Continent Urinary Diversion.

Jefferson FA, Carmel ME.

ReviewOpen access

AI summary — for doctors, generated from the abstract only

Continent urinary diversion is a durable option for end-stage neurogenic bladder refractory to less invasive therapy.

What was studied

Literature review on the role of continent urinary diversion (such as Indiana pouch) in refractory neurogenic lower urinary tract dysfunction with a poorly compliant bladder.

Key findings

  • It creates a low-pressure, high-capacity reservoir and removes the hostile bladder and outlet.
  • It offers continence without an external appliance compared with ileal conduit.
  • Complication and revision rates are meaningful and lifelong follow-up is required.

Clinical relevance

Gives urologists a framework to consider definitive reconstruction for upper tract protection and quality of life.

Who should care

Urology

Limitations

A narrative literature review advocating a position, likely from selected series, with no pooled comparisons in the abstract.

Consider continent diversion in well-selected patients who fail minimally invasive therapy and can commit to lifelong surveillance.

This is an AI-generated summary of the published abstract, not a clinical recommendation. It may not reflect the full text or subsequent updates — verify against the original source before acting on it.

Abstract

Introduction

Neurogenic lower urinary tract dysfunction (NLUTD) with a poorly compliant bladder that is refractory to minimally invasive therapies (MIT) represents an "end-stage" phenotype in which the principal objectives are durable upper urinary tract protection and restoration of continence with acceptable long-term morbidity. For most surgically eligible patients in this setting, continent urinary diversion-most commonly a continent cutaneous catheterizable reservoir (e.g., Indiana pouch) and, in highly selected cases, an orthotopic continent diversion-offers a uniquely definitive strategy.

Methods

We conducted a literature review to better characterize the role of continent urinary diversion in the management of refractory NLUTD.

Results

Continent diversion creates a low-pressure, high-capacity urinary reservoir while bypassing and often removing the hostile native bladder and dysfunctional outlet, thereby reducing ongoing pelvic urinary morbidity and the surveillance dilemmas inherent to augmentation enterocystoplasty. Compared with an ileal conduit, continent diversion prioritizes continence without an external appliance, an outcome strongly aligned with independence, body image, and sexual well-being in many neuro-urological patients.

Conclusion

Although complication and revision rates are meaningful and the need for lifelong follow-up remains, contemporary long-term series support durability, preserved renal function, and high satisfaction when patient selection and structured surveillance are optimized.

DOI

10.1002/nau.70347

PMID

42403149

Research metadata (titles, abstracts, authors, publication dates) is sourced from Europe PMC, which aggregates content from PubMed/MEDLINE, PubMed Central, and other providers under the U.S. National Library of Medicine (NLM/NCBI). NLM does not claim copyright on abstracts; the original journal publishers or authors may hold rights to the full articles. AI-generated summaries are derived only from the abstract, never the full text, and are always labeled as AI-generated.

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