Long-Term Functional Outcomes and Complications of AdVance™/AdVance XP™ Male Suburethral Slings in the Management of Post-Prostatectomy Incontinence: Multicentric Prospective Ten-Year Follow-Up Study.

Collado A, Folkersma LR, Romero A, +6 more, Gomez-Ferrer A.

Observational StudyAbstract only — full text under license

AI summary — for doctors, generated from the abstract only

Ten years after AdVance male sling placement, about two-thirds were initially cured and nearly 29% of those later lost continence.

What was studied

Multicenter prospective observational study of 111 men with post-prostatectomy incontinence who received AdVance or AdVance XP slings, with 87 completing 10-year follow-up using 24-hour pad tests and ICIQ-SF.

Key findings

67.8% were cured at 3 months.
28.8% of the cured lost continence over time, mostly from recurrent SUI (65%), de novo urge incontinence (23%) or salvage radiotherapy (12%).
Six of the 17 had a second surgery; median ICIQ-SF in cured patients fell from 16.27 to 4.03.

Clinical relevance

Provides durable data for counseling about the sling in men with mild-to-moderate incontinence.

Who should care

Urology

Limitations

Loss of 24 of 111 patients to follow-up and an observational design without a control group.

Offer the sling to men with mild-to-moderate incontinence and no prior radiation or incontinence surgery, with counseling about late recurrence.

This is an AI-generated summary of the published abstract, not a clinical recommendation. It may not reflect the full text or subsequent updates — verify against the original source before acting on it.

Abstract

Introduction

Male sling implants are an acceptable treatment for post-prostatectomy stress urinary incontinence, but more long-term follow data is needed to assess clinical effectiveness. This study provides long-term continence and quality of life outcomes using complete 10-year follow up data from patients with AdVance™/AdVance XP™ Male Sling Systems.

Methods

In an observational multicenter study, prospective data collection included preoperative patient characteristics, perioperative course, and postoperative outcomes. Continence was assessed using the 24 h pad weight test and patient-reported outcome measures (PROMs) were measured with the International Consultation on Incontinence Questionnaire Short Form (ICIQ-UI SF). Follow-up over 10 years included re-intervention.

Results

Of 111 patients who underwent surgery between February 2008 and February 2012, 87 completed 10-year follow-up (median follow-up was 136.6 months (range:121.9-170.5). At 3-month follow-up, 59 patients (67.8%) were considered cured. Of the 59 patients initially cured, 17 patients (28.81%) lost continence during follow-up, 11 due to stress urinary incontinence recurrence (65%), four due to de novo urge incontinence (23%), and two due to salvage radiotherapy (12%). Of the 17 who lost continence, six received a second surgical treatment, with no reported intra or preoperative surgical problems due to the first surgery. In cured patients, surgery resulted in a reduction of the median ICIQ-SF score from 16.27 (SD 3.53) to 4.03 (SD 3.36) (p < 0.01). In the patients considered not cured, a reduction on the median ICIQ-SF score from 16.39 (SD 3.05) to 11.29 (SD 5.34) was observed (p < 0.01).

Conclusions

Our findings suggest that long-term continence rates after sling implant are acceptable, especially in ideal patients with mild to moderate incontinence and naïve for prior pelvic irradiation or surgical treatment for urinary incontinence or urethral stricture disease.

DOI

10.1002/nau.70341

PMID

42318865

Research metadata (titles, abstracts, authors, publication dates) is sourced from Europe PMC, which aggregates content from PubMed/MEDLINE, PubMed Central, and other providers under the U.S. National Library of Medicine (NLM/NCBI). NLM does not claim copyright on abstracts; the original journal publishers or authors may hold rights to the full articles. AI-generated summaries are derived only from the abstract, never the full text, and are always labeled as AI-generated.

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